Redefining
early-stage
therapeutics

i.
Therapeutics
only
ii.
Pre-Seed
→ Seed
iii.
$500k - $1.5m
first check
iv.
Disease Indication Modality
agnostic
v.
Proof of Concept
minimum
§ 01 — Who we are

Mitre Ventures supports early-stage US life science startups developing transformative therapeutics.

We bridge visionary founders with mission-aligned investors bringing deep domain expertise, a strong advisory network, and a founder-first philosophy to every check we write.

§ 02

Our investment thesis.

01 / 05Sector
Therapeutics
only.

We invest exclusively in therapeutics. Oncology, CNS, infectious disease, women's health, along with may others. If the endpoint is a patient outcome, we want to talk.

02 / 05Round
Pre-Seed
→ Seed.

Early-stage, dilutive funding when the science is real and the timing is right.

03 / 05Disease
Agnostic.

Multi-platform therapeutics. Scalable pipelines. Diversified risk.

04 / 05Indication
Agnostic.

Indications across the full spectrum, aligned with the strengths of the platform.

05 / 05Modality
Agnostic.

CAR-T, CGT, mRNA, ASO, small molecules. The mechanism is yours to choose.

§ 03

Our portfolio.

§ 04

Founder & GP

F. Matthew Bakthasekaran
F. Matthew
Bakthasekaran MBA
Founder & General Partner · Chattanooga, TN

I ’m a seasoned entrepreneur, investor, and project manager with over 20 years of leadership experience spanning multiple industries, including construction and bio-pharmaceuticals. My journey began in the construction sector, where I successfully built and operated my own business before transitioning into clinical trial management. Since then, I’ve led complex projects within both global corporations and agile, fast-growing startups.

My expertise lies in driving operational excellence, optimizing financial performance, and navigating the regulatory complexities of the life sciences industry. I bring a diverse skill set that includes project management, business development, finance, data analytics, risk assessment, and strategic oversight, enabling organizations to scale efficiently and deliver results.

I hold a Bachelor of Science In Public Health (BPH) and a Master In Business Administration (MBA), providing a strong foundation in both healthcare and business strategy. Outside of work, I’m a proud father to two beautiful daughters and a devoted husband, enjoying life in Chattanooga and all it has to offer. I actively serve in leadership of our men’s ministry team at Signal Mountain Bible Church and support my wife in her work with RUF Ministries, finding joy and purpose in both family and faith.

§ 05

Advisory Board

Craig Pierson
Craig Pierson
Advisor Chair
Sal Filardi
Sal Filardi
Advisor
Tim Foley
Tim Foley
Advisor
Krystle Karoscik
Krystle Karoscik
Advisor
Vivian Rodolf
Vivian Rodolf
Advisor
§ 06 — Network

Built on relationships that compound.

We work alongside leading venture builders and ecosystem partners to source, validate, and accelerate the next generation of therapeutics companies.

Nucleate
LaunchTN
§ 07 — Fund I

Now fundraising.

Mitre Ventures Fund I is open to qualified Limited Partners. If you're a mission-aligned investor exploring exposure to early-stage therapeutics, we welcome the conversation.

Fund I · Fundraising